By Brand > Agilent Technologies > Liquid Chromatography > 6230B Time of Flight (TOF) LC/MS

6230B Time of Flight (TOF) LC/MS

The Agilent 6230B time-of-flight LC/MS (LC/TOF) system allows you to upgrade from nominal mass measurements to a high-resolution accurate mass (HRAM) system for vastly enhanced analytical capabilities. Simultaneous measurement of the full spectrum of mass-to-charge ratios up to 20,000 improves speed and facilitates greater sensitivity. The full mass spectrum scan of a TOF LC/MS ensures that all necessary information is captured to enable screening, identification of unknowns, advanced statistical analysis, and biomolecule characterization. High resolving power allows for the separation of complex mixtures and aids in the determination of elemental formulae.

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6230B Time of Flight (TOF) LC/MS

Product Details

Features
  • Reduce false positives with better than 1 ppm mass accuracy
  • Ensure excellent data quality even for fast UHPLC peaks in high-throughput workflows with data acquisition rates up to 44 spectra/second
  • Identify compounds based on accurate mass, isotopic abundance, and chemical composition using Find by Formula in MassHunter software
  • Analyze monoclonal antibodies (mAb) with high mass accuracy and resolving power for glycoforms and truncation
  • Characterize large biologic compounds with a broad mass range of up to 20,000 m/z
  • Separate target compounds from interferences with high-resolution data
  • Find impurities at extremely low concentrations, using Agilent Jet Stream technology with low picogram on-column sensitivity
  • Identify trace-level target compounds in the presence of more abundant matrix compounds with up to five orders of in-spectrum dynamic range
  • Reduce administrative tasks and risks while eliminating the need for LC/MS expertise with intuitive MassHunter Walkup software
  • Perform untargeted screening with optional fragmentation data using in-source dissociation
  • Reduce administrative tasks and risks while eliminating the need for LC/MS expertise with intuitive MassHunter WalkUp software
  • Go beyond UHPLC separation with support for capillary electrophoresis, SFC, 2D-LC, and even GC-APCI chromatographic interfaces.

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