Q: How It Works

The same power as a traditional LC/TQ in a stackable bench-saving system The Ultivo footprint is 70% smaller than that of similar LC/TQ systems, but it gives you the same performance! Read on about the innovations that make Ultivo a miniature mass spectrometer powerhouse. The Cyclone Ion Guide is a dual-field hexa-dodecapole comprised of an outer and inner hexapole providing efficient confinement and transmission of ions across the m/z range. High performance is achieved through a twist that introduces a dramatic taper to compress the ion beam for maximum transmission while shortening the path length – enabling the compact design of Ultivo. Innovative quadrupole pre-filter design allows miniaturization at the same sensitivity Another dramatic source of miniaturization comes from the use of DC-only virtual pre and post filters. Roughly 1 mm in thickness, they directly align with the hyperbolic quadrupoles to eliminate fringe field effects for incoming ions. Traditional Brubaker pre and post filters are typically 2–3 cm long, but the innovative Agilent quadrupole pre-filter design results in a 99.5% reduction in size while maintaining high instrument performance. Increase sample throughput with faster scanning combined with high confidence Like the Cyclone Ion guide, the Vortex Collision Cell features a unique rod geometry that is twisted and tapered. However, instead of hosting outer rods, a single monopole sheath is used to augment the hexapolar RF fields. This unique geometry reduces ion scattering and eliminates trapping after collision induced dissociation (CID) by allowing ions to be recaptured and collimated/compressed into a tight beam. This results in excellent fragmentation efficiency, fragmentation fidelity, and transmission efficiency into the MS2 quadrupole.

Q: Applications

Detecting Unsafe and Adulterated Honey Honey provides nutrition, imparts sweetness, and has interesting chemical properties. With high demand, unscrupulous actors attempt to maximize yield by treating honeybees with antibiotics, or by diluting honey with other plant-based syrups. As a result, food agencies strictly regulate the production of honey to monitor and limit the use of chemicals and other adulterations. The Ultivo LC/TQ is perfectly suited for honey testing, providing robust and sensitive food inspection and authenticity analysis. Look here for honey testing methods with the Ultivo LC/TQ.

Question 1

Features

Accepted Answer

Smallest footprint of any LC/TQ on the market, delivering a price/performance per square foot ratio that leads to reduced costs and the fastest path to achieving ROI
Multiple ion source configurations available, including Agilent Jet Stream and traditional ESI
VacShield eliminates the need to vent the system while performing ion injector maintenance, minimizing maintenance downtime and increasing laboratory efficiency
Cyclone ion guide compresses the ion beam without loss of signal, resulting in higher ion transmission efficiencies and enhanced data quality
Vortex collision cell provides efficient dissociation of ions in the cell, improved focusing and transmission of ions, and rapid clearance of the cell between mass transitions, thereby allowing for more MRMs/sec, zero crosstalk, and greater confidence in results by removing noisy background
Screen, confirm, and quantitate with triggered MRM (tMRM), which combines fast and sensitive MRM quantitation with the generation of a product ion spectrum for compound screening and confirmation
Intuitive &#8216;Quant-My-Way&#8217; software and the MassHunter Productivity App boost productivity by up to 40%, require less need for operator training, reduce time spent reviewing data, and simplify report generation
Enhanced maintenance feedback (EMF) features deliver smart, self-aware diagnostics to ensure optimum uptime and help drive down maintenance costs
Built-in technical controls combined with procedural controls ensure the security of your data, control access, and facilitate compliance as defined by US FDA 21 CFR Part 11, EU Annex 11 and similar national electronic record regulations

Question 2

Specifications

Accepted Answer

Collision Cell Clearance Time

<1 ms

Dimensions (WxDxH)

32 cm x 88 cm x 39.5 cm

IDL Sensitivity (positive)

<20 fg Reserpine on-column, <20 ppt
IDL spec only for new LC/MS systems using Agilent Jet Stream + checkout column + 1290 Infinity II LC

Instrument Health Tracking

Early Maintenance Feedback System

Ion Source

ESI
AJS
APCI

MRM Speed

500 MRM transitions/s

Mass Range

m/z 5-1400

Minimum MRM Dwell Time

1 ms

Polarity Switch Speed

<20 ms

Quad Resolution (FWHM)

Unit = 0.7 Da
Wide = 1.2 Da
Widest = 2.5 Da

Scan Speed

15000 Da/s

Question 3

How It Works

Accepted Answer

The same power as a traditional LC/TQ in a stackable bench-saving system
The Ultivo footprint is 70% smaller than that of similar LC/TQ systems, but it gives you the same performance! Read on about the innovations that make Ultivo a miniature mass spectrometer powerhouse.
The Cyclone Ion Guide is a dual-field hexa-dodecapole comprised of an outer and inner hexapole providing efficient confinement and transmission of ions across the m/z range.
High performance is achieved through a twist that introduces a dramatic taper to compress the ion beam for maximum transmission while shortening the path length – enabling the compact design of Ultivo.
Innovative quadrupole pre-filter design allows miniaturization at the same sensitivity
Another dramatic source of miniaturization comes from the use of DC-only virtual pre and post filters. Roughly 1 mm in thickness, they directly align with the hyperbolic quadrupoles to eliminate fringe field effects for incoming ions.
Traditional Brubaker pre and post filters are typically 2–3 cm long, but the innovative Agilent quadrupole pre-filter design results in a 99.5% reduction in size while maintaining high instrument performance.
Increase sample throughput with faster scanning combined with high confidence
Like the Cyclone Ion guide, the Vortex Collision Cell features a unique rod geometry that is twisted and tapered. However, instead of hosting outer rods, a single monopole sheath is used to augment the hexapolar RF fields.
This unique geometry reduces ion scattering and eliminates trapping after collision induced dissociation (CID) by allowing ions to be recaptured and collimated/compressed into a tight beam. This results in excellent fragmentation efficiency, fragmentation fidelity, and transmission efficiency into the MS2 quadrupole.

Question 4

Applications

Accepted Answer

Detecting Unsafe and Adulterated Honey
Honey provides nutrition, imparts sweetness, and has interesting chemical properties. With high demand, unscrupulous actors attempt to maximize yield by treating honeybees with antibiotics, or by diluting honey with other plant-based syrups. As a result, food agencies strictly regulate the production of honey to monitor and limit the use of chemicals and other adulterations. The Ultivo LC/TQ is perfectly suited for honey testing, providing robust and sensitive food inspection and authenticity analysis.
Look here for honey testing methods with the Ultivo LC/TQ.

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Ultivo Triple Quadrupole LC/MS

Ultivo Triple Quadrupole LC/MS

Product Details

The same power as a traditional LC/TQ in a stackable bench-saving system

Innovative quadrupole pre-filter design allows miniaturization at the same sensitivity

Increase sample throughput with faster scanning combined with high confidence

Detecting Unsafe and Adulterated Honey

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